Four mayors from European and Russian border regions are joining the 18th European Week of Regions and Cities to share their stories of cooperation in various fields, from tourism to border management and mobility, from culture to protection of natural resources. For over 10 years cross-border cooperation between the EU and Russia has fostered hundreds of projects, contributing to the improvement of life conditions for hundreds of thousands of people. Over 30% of project beneficiaries are represented by local and regional authorities. Building on the successful experience of the ENPI period, many local and regional administrations in Finland, Estonia, Latvia, Lithuania, Poland and Russia continue their cooperation under the current generation of the Neighbourhood (ENI CBC) programmes, already preparing the ground for the next programming cycle (Interreg NEXT). Our workshop will showcase how CBC projects can build long-lasting relations between local and regional authorities across the borders. The mayors will be introduced by the interventions from the four programme representatives.